The (6-3) are favored by 12 points versus the (4-5) on November 19, 2023, starting at 4:05 PM ET, airing on FOX. The matchup has an over/under of 41 points. Odds & Betting Lines49ers vs Buccaneers Betting Information updated as of November 15, 2023, 12:33 PM ET.FavoriteSpreadFavorite Spread OddsUnderdog Spread OddsTotalOver Total OddsUnder Total Odds49ers-12-108-11241-115-105ADVERTISEMENT 49ers vs. Buccaneers Prediction & PickPick ATS: San Francisco (-12)Pick OU: Over (41)Prediction: San Francisco 28 - Tampa Bay 14How to Watch San Francisco vs. Tampa BayGame Date: Sunday, November 19, 2023Time: 4:05 PM ETVenue: Levi's StadiumLocation: Santa Clara, CaliforniaTV: Watch on FOX49ers vs. Buccaneers Adam Clendening Men Jersey Recent MatchupsOver their last five meetings, San Francisco has collected three wins versus Tampa Bay.Over their last five head-to-head matchups, San Francisco has scored 125 points, while Tampa Bay has posted 99.San Francisco Betting InfoSan Francisco is 5-4-0 against the spread this year.The 49ers have been favored by 12 points or more once this season, and covered the spread.San Francisco games this year have gone over the total in four out of nine opportunities (44.4%).When playing as moneyline favorites, the 49ers have won 66.7% NHL Columbus Blue Jackets Women Jersey of the time (6-3).San Francisco has played as a moneyline favorite of -600 or shorter in only one game this season, which it won.Based on this matchup's moneyline, the 49ers' implied win probability is 85.7%.49ers StatsStatAverage (Total)RankPa s yards248.7 (2,238)9Rush yards134.7 (1,212)6Points scored28.0 (252)5Pa s yards against221.4 (1,993)15Rush yards against83.1 (748)4Points allowed15.9 (143)2San Francisco's Key PlayersOffenseChristian McCaffrey has totaled 747 rushing yards (first in the NFL) with nine touchdowns (83.0 yards per game through nine games). His 4.9 yards per attempt rank seventh in the NFL.McCaffrey has 47 targets, 38 receptions, 339 receiving yards and four TDs in the pa sing game. has 2,329 pa sing yards, 15 touchdowns (ninth in the NFL) and five interceptions this year. He has completed 68.8% of his pa ses, averaging 258.8 yards per game and 9.3 per attempt.He has tacked on 107 rushing yards (11.9 per game) and two touchdowns on the ground. has three touchdown catches this season, and has 38 catches for 675 yards on 55 targets, while averaging 4.8 catches and 84.4 yards per game. has 35 receptions for 559 yards and four touchdowns. He's been targeted 47 times in the pa sing game, and averages 3.9 receptions and 62.1 yards in nine games played.DefenseOn defense, has 78 tackles, 5.0 TFL, two sacks, and three interceptions in 2023. His tackle total leads the 49ers. has 25 tackles, 7.0 TFL, and 4.5 sacks this season. has put up 63 tackles, 5.0 TFL, and one sack this Curtis McElhinney Jersey year.This season, has 50 tackles, 1.0 TFL, and three interceptions.Tampa Bay Betting InfoTampa Bay is 6-3-0 against the spread this season.This season, Tampa Bay games have hit the over twice.This season, the Buccaneers have been the underdog six times and won two of those games.Tampa Bay has not entered a game this season with longer moneyline odds than + Scott Harrington Men Jersey 440.Oddsmakers have implied with the moneyline set for this matchup that the Buccaneers have a 18.5% chance to win.Buccaneers StatsStatAverage (Total)RankPa s yards228.6 (2,057)15Rush yards78.1 (703)31Points scored19.8 (178)23Pa s yards against266.9 (2,402)31Rush yards against87.2 (785)6Points allowed19.2 (173)8Tampa Bay's Key PlayersOffenseIn nine games played this year, has totaled 2,143 pa sing yards, while throwing 14 touchdowns against five interceptions and completing 64.6% of his pa ses.Mayfield has also rushed for 134 yards (second on the Buccaneers). has 737 receiving yards (10th in the NFL) and six touchdowns (fifth in the NFL) on 43 receptions, while being targeted 70 times. is averaging 47.7 rushing yards per game this season (429 total yards), while scoring three rushing touchdowns.In addition to his ground game, White has grabbed 35 pa ses (on 37 targets) for 326 yards (third on the Buccaneers), with one receiving touchdown. He averages 36.2 yards per game. has 44 catches for 522 yards and one receiving touchdown. He averages 4.9 yards per game in Josh Anderson Kids Jersey nine games and has been targeted 68 times.DefenseLavonte David has 83 tackles, 11.0 TFL, two sacks, and three pa ses defended in 2023.. has one interception on top of 55 tackles, 2.0 TFL, two sacks, and seven pa ses defended. has 60 tackles, 3.0 TFL, two sacks, and one interception in the 2023 campaign. He is second on the Buccaneers in tackles. has totaled 4.0 sacks (second on the Buccaneers) to go with 2.0 TFL, 31 tackles, and one interception over nine games.